Search Results
Overview
| Uniprot ID | P55083 |
|---|---|
| Protein Name | Microfibril-associated glycoprotein 4 |
| Gene Name | MFAP4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 100 | FRGWNDYKLGFGRAD |
| 246 | KGFYYSLKRTEMKIR |
| 84 | GKWTVFQKRFNGSVS |
Function
Could be involved in calcium-dependent cell adhesion or intercellular interactions. May contribute to the elastic fiber assembly and/or maintenance (PubMed:26601954)
Protein Sequence
10
MKALLALPLL
20
LLLSTPPCAP
30
QVSGIRGDAL
40
ERFCLQQPLD
50
CDDIYAQGYQ
60
SDGVYLIYPS
70
GPSVPVPVFC
80
DMTTEGGKWT
90
VFQKRFNGSV
100
SFFRGWNDYK
110
LGFGRADGEY
120
WLGLQNMHLL
130
TLKQKYELRV
140
DLEDFENNTA
150
YAKYADFSIS
160
PNAVSAEEDG
170
YTLFVAGFED
180
GGAGDSLSYH
190
SGQKFSTFDR
200
DQDLFVQNCA
210
ALSSGAFWFR
220
SCHFANLNGF
230
YLGGSHLSYA
240
NGINWAQWKG
250
FYYSLKRTEM
KIRRA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071953 | elastic fiber |
| Cellular Component | GO:0031012 | extracellular matrix |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0001527 | microfibril |
| Biological Process | GO:0007155 | cell adhesion |
| Biological Process | GO:0071493 | cellular response to UV-B |
| Biological Process | GO:0048251 | elastic fiber assembly |
| Biological Process | GO:0010712 | regulation of collagen metabolic process |
| Biological Process | GO:0097435 | supramolecular fiber organization |
| Biological Process | GO:0009650 | UV protection |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.