Search Results
Overview
| Uniprot ID | P55795 |
|---|---|
| Protein Name | Heterogeneous nuclear ribonucleoprotein H2 |
| Gene Name | HNRNPH2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 349 | VAAMAKDKANMQHRY |
Function
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG)
Protein Sequence
10
MMLSTEGREG
20
FVVKVRGLPW
30
SCSADEVMRF
40
FSDCKIQNGT
50
SGIRFIYTRE
60
GRPSGEAFVE
70
LESEEEVKLA
80
LKKDRETMGH
90
RYVEVFKSNS
100
VEMDWVLKHT
110
GPNSPDTAND
120
GFVRLRGLPF
130
GCSKEEIVQF
140
FSGLEIVPNG
150
MTLPVDFQGR
160
STGEAFVQFA
170
SQEIAEKALK
180
KHKERIGHRY
190
IEIFKSSRAE
200
VRTHYDPPRK
210
LMAMQRPGPY
220
DRPGAGRGYN
230
SIGRGAGFER
240
MRRGAYGGGY
250
GGYDDYGGYN
260
DGYGFGSDRF
270
GRDLNYCFSG
280
MSDHRYGDGG
290
SSFQSTTGHC
300
VHMRGLPYRA
310
TENDIYNFFS
320
PLNPMRVHIE
330
IGPDGRVTGE
340
ADVEFATHED
350
AVAAMAKDKA
360
NMQHRYVELF
370
LNSTAGTSGG
380
AYDHSYVELF
390
LNSTAGASGG
400
AYGSQMMGGM
410
GLSNQSSYGG
420
PASQQLSGGY
430
GGGYGGQSSM
440
SGYDQVLQEN
SSDYQSNLA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
| Biological Process | GO:0043484 | regulation of RNA splicing |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Molecular Function | GO:0003723 | RNA binding |
Reference
[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.