Search Results
Overview
| Uniprot ID | P56182 |
|---|---|
| Protein Name | Ribosomal RNA processing protein 1 homolog A |
| Gene Name | RRP1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 446 | PLTSARAKAANVQEP |
| 457 | VQEPEKKKKRRE*** |
Function
Plays a critical role in the generation of 28S rRNA
Protein Sequence
10
MVSRVQLPPE
20
IQLAQRLAGN
30
EQVTRDRAVR
40
KLRKYIVART
50
QRAAGGFTHD
60
ELLKVWKGLF
70
YCMWMQDKPL
80
LQEELGRTIS
90
QLVHAFQTTE
100
AQHLFLQAFW
110
QTMNREWTGI
120
DRLRLDKFYM
130
LMRMVLNESL
140
KVLKMQGWEE
150
RQIEELLELL
160
MTEILHPSSQ
170
APNGVKSHFI
180
EIFLEELTKV
190
GAEELTADQN
200
LKFIDPFCRI
210
AARTKDSLVL
220
NNITRGIFET
230
IVEQAPLAIE
240
DLLNELDTQD
250
EEVASDSDES
260
SEGGERGDAL
270
SQKRSEKPPA
280
GSICRAEPEA
290
GEEQAGDDRD
300
SGGPVLQFDY
310
EAVANRLFEM
320
ASRQSTPSQN
330
RKRLYKVIRK
340
LQDLAGGIFP
350
EDEIPEKACR
360
RLLEGRRQKK
370
TKKQKRLLRL
380
QQERGKGEKE
390
PPSPGMERKR
400
SRRRGVGADP
410
EARAEAGEQP
420
GTAERALLRD
430
QPRGRGQRGA
440
RQRRRTPRPL
450
TSARAKAANV
460
QEPEKKKKRR
E
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0030688 | preribosome, small subunit precursor |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0003713 | transcription coactivator activity |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
| Biological Process | GO:0006364 | rRNA processing |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.