Search Results
Overview
| Uniprot ID | P57076 |
|---|---|
| Protein Name | Cilia- and flagella-associated protein 298 |
| Gene Name | CFAP298 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 283 | KRHFHGVKDIKWRPR |
Function
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:24094744). Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity)
Protein Sequence
10
MVLLHVKRGD
20
ESQFLLQAPG
30
STELEELTVQ
40
VARVYNGRLK
50
VQRLCSEMEE
60
LAEHGIFLPP
70
NMQGLTDDQI
80
EELKLKDEWG
90
EKCVPSGGAV
100
FKKDDIGRRN
110
GQAPNEKMKQ
120
VLKKTIEEAK
130
AIISKKQVEA
140
GVCVTMEMVK
150
DALDQLRGAV
160
MIVYPMGLPP
170
YDPIRMEFEN
180
KEDLSGTQAG
190
LNVIKEAEAQ
200
LWWAAKELRR
210
TKKLSDYVGK
220
NEKTKIIAKI
230
QQRGQGAPAR
240
EPIISSEEQK
250
QLMLYYHRRQ
260
EELKRLEEND
270
DDAYLNSPWA
280
DNTALKRHFH
290
GVKDIKWRPR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Biological Process | GO:0060271 | cilium assembly |
| Biological Process | GO:0003352 | regulation of cilium movement |
Reference
PMID: N/A