Search Results
Overview
| Uniprot ID | P57784 |
|---|---|
| Protein Name | U2 small nuclear ribonucleoprotein A' |
| Gene Name | Snrpa1 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 172 | KRGAQLAKDIARRSK |
| 179 | KDIARRSKTFNPGAG |
Function
Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA
Protein Sequence
10
MVKLTAELIE
20
QAAQYTNAVR
30
DRELDLRGYK
40
IPVIENLGAT
50
LDQFDAIDFS
60
DNEIRKLDGF
70
PLLRRLKTLL
80
VNNNRICRIG
90
EGLDQALPCL
100
TELILTNNSL
110
VELGDLDPLA
120
SLKSLTYLSI
130
LRNPVTNKKH
140
YRLYVIYKVP
150
QVRVLDFQKV
160
KLKERQEAEK
170
MFKGKRGAQL
180
AKDIARRSKT
190
FNPGAGLPTD
200
KKKGGPSAGD
210
VEAIKNAIAN
220
ASTLAEVERL
230
KGLLQSGQIP
240
GRERRSGPSD
250
EGEEEIEDDT
VTNGS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Biological Process | GO:0007283 | spermatogenesis |
| Cellular Component | GO:0016604 | nuclear body |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0071014 | post-mRNA release spliceosomal complex |
| Cellular Component | GO:0071020 | post-spliceosomal complex |
| Cellular Component | GO:0071011 | precatalytic spliceosome |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Cellular Component | GO:0005686 | U2 snRNP |
| Cellular Component | GO:0071006 | U2-type catalytic step 1 spliceosome |
| Cellular Component | GO:0071007 | U2-type catalytic step 2 spliceosome |
| Cellular Component | GO:0071005 | U2-type precatalytic spliceosome |
| Cellular Component | GO:0005684 | U2-type spliceosomal complex |
| Molecular Function | GO:0030620 | U2 snRNA binding |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.