Search Results
Overview
| Uniprot ID | P59773 |
|---|---|
| Protein Name | Major intrinsically disordered NOTCH2-binding receptor 1-like |
| Gene Name | MINAR2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 59 | VYSQREKKNIAAQRI |
Function
Binds cholesterol and may regulate the distribution and homeostasis of cholesterol in hair cells (PubMed:36317962). May play a role in angiogenesis (PubMed:35727972)
Protein Sequence
10
MDLSVLPNNN
20
HPDKFLQLDV
30
KSLTRSSALL
40
QASLVRFPGG
50
NYPAAQHWQN
60
LVYSQREKKN
70
IAAQRIRGSS
80
ADSLVTADSP
90
PPSMSSVMKN
100
NPLYGDLSLE
110
EAMEERKKNP
120
SWTIEEYDKH
130
SLHTNLSGHL
140
KENPNDLRFW
150
LGDMYTPGFD
160
TLLKKEEKQE
170
KHSKFCRMGL
180
ILLVVISILV
190
TIVTIITFFT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0005765 | lysosomal membrane |
| Cellular Component | GO:0032420 | stereocilium |
| Molecular Function | GO:0015485 | cholesterol binding |
| Biological Process | GO:0001525 | angiogenesis |
| Biological Process | GO:0042632 | cholesterol homeostasis |
Reference
[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.