Search Results
Overview
| Uniprot ID | P59780 |
|---|---|
| Protein Name | AP-3 complex subunit sigma-2 |
| Gene Name | AP3S2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 166 | ARAVSAVKNINLPEI |
Function
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals
Protein Sequence
10
MIQAILVFNN
20
HGKPRLVRFY
30
QRFPEEIQQQ
40
IVRETFHLVL
50
KRDDNICNFL
60
EGGSLIGGSD
70
YKLIYRHYAT
80
LYFVFCVDSS
90
ESELGILDLI
100
QVFVETLDKC
110
FENVCELDLI
120
FHMDKVHYIL
130
QEVVMGGMVL
140
ETNMNEIVAQ
150
IEAQNRLEKS
160
EGGLSAAPAR
170
AVSAVKNINL
180
PEIPRNINIG
190
DLNIKVPNLS
QFV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030123 | AP-3 adaptor complex |
| Cellular Component | GO:1904115 | axon cytoplasm |
| Cellular Component | GO:0030659 | cytoplasmic vesicle membrane |
| Cellular Component | GO:0005769 | early endosome |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0008021 | synaptic vesicle |
| Biological Process | GO:0008089 | anterograde axonal transport |
| Biological Process | GO:0048490 | anterograde synaptic vesicle transport |
| Biological Process | GO:0035654 | clathrin-coated vesicle cargo loading, AP-3-mediated |
| Biological Process | GO:0006896 | Golgi to vacuole transport |
| Biological Process | GO:0006886 | intracellular protein transport |
| Biological Process | GO:1903232 | melanosome assembly |
| Biological Process | GO:0060155 | platelet dense granule organization |
| Biological Process | GO:0016183 | synaptic vesicle coating |
| Biological Process | GO:0036465 | synaptic vesicle recycling |
| Biological Process | GO:0016192 | vesicle-mediated transport |
Reference
PMID: N/A