Search Results
Overview
| Uniprot ID | P60905 |
|---|---|
| Protein Name | DnaJ homolog subfamily C member 5 |
| Gene Name | Dnajc5 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 46 | ALKYHPDKNPDNPEA |
| 56 | DNPEAADKFKEINNA |
Function
Acts as a general chaperone in regulated exocytosis (By similarity). Acts as a co-chaperone for the SNARE protein SNAP-25 (By similarity). Involved in the calcium-mediated control of a late stage of exocytosis (By similarity). May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity)
Protein Sequence
10
MADQRQRSLS
20
TSGESLYHVL
30
GLDKNATSDD
40
IKKSYRKLAL
50
KYHPDKNPDN
60
PEAADKFKEI
70
NNAHAILTDA
80
TKRNIYDKYG
90
SLGLYVAEQF
100
GEENVNTYFV
110
LSSWWAKALF
120
VVCGLLTCCY
130
CCCCLCCCFN
140
CCCGKCKPKA
150
PEGEETEFYV
160
SPEDLEAQLQ
170
SDEREATDTP
180
IVIQPASATE
190
TTQLTADSHP
SYHTDGFN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0042584 | chromaffin granule membrane |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0042470 | melanosome |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0031594 | neuromuscular junction |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098793 | presynapse |
| Cellular Component | GO:0008021 | synaptic vesicle |
| Cellular Component | GO:0030672 | synaptic vesicle membrane |
| Cellular Component | GO:0043195 | terminal bouton |
| Molecular Function | GO:0043008 | ATP-dependent protein binding |
| Biological Process | GO:0007268 | chemical synaptic transmission |
| Biological Process | GO:0043524 | negative regulation of neuron apoptotic process |
| Biological Process | GO:0006457 | protein folding |
| Biological Process | GO:0098693 | regulation of synaptic vesicle cycle |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.