Search Results
Overview
| Uniprot ID | P60982 |
|---|---|
| Protein Name | Destrin |
| Gene Name | DSTN |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 132 | KKKFQGIKHECQANG |
| 19 | CRIFYDMKVRKCSTP |
| 22 | FYDMKVRKCSTPEEI |
| 30 | CSTPEEIKKRKKAVI |
| 44 | IFCLSADKKCIIVEE |
| 45 | FCLSADKKCIIVEEG |
| 78 | FVGMLPEKDCRYALY |
| 92 | YDASFETKESRKEEL |
Function
Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner
Protein Sequence
10
MASGVQVADE
20
VCRIFYDMKV
30
RKCSTPEEIK
40
KRKKAVIFCL
50
SADKKCIIVE
60
EGKEILVGDV
70
GVTITDPFKH
80
FVGMLPEKDC
90
RYALYDASFE
100
TKESRKEELM
110
FFLWAPELAP
120
LKSKMIYASS
130
KDAIKKKFQG
140
IKHECQANGP
150
EDLNRACIAE
160
KLGGSLIVAF
EGCPV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0030864 | cortical actin cytoskeleton |
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0051015 | actin filament binding |
| Biological Process | GO:0030043 | actin filament fragmentation |
| Biological Process | GO:0051014 | actin filament severing |
| Biological Process | GO:0030836 | positive regulation of actin filament depolymerization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.