Search Results
Overview
| Uniprot ID | P61265 |
|---|---|
| Protein Name | Syntaxin-1B |
| Gene Name | Stx1b |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 125 | QHSTLSRKFVEVMTE |
| 188 | KMDSQMTKQALNEIE |
| 203 | TRHNEIIKLETSIRE |
| 45 | EIRGCIEKLSEDVEQ |
| 54 | SEDVEQVKKQHSAIL |
| 55 | EDVEQVKKQHSAILA |
| 69 | AAPNPDEKTKQELED |
| 71 | PNPDEKTKQELEDLT |
| 82 | EDLTADIKKTANKVR |
Function
Potentially involved in docking of synaptic vesicles at presynaptic active zones (PubMed:7901002). May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity)
Protein Sequence
10
MKDRTQELRS
20
AKDSDDEEEV
30
VHVDRDHFMD
40
EFFEQVEEIR
50
GCIEKLSEDV
60
EQVKKQHSAI
70
LAAPNPDEKT
80
KQELEDLTAD
90
IKKTANKVRS
100
KLKAIEQSIE
110
QEEGLNRSSA
120
DLRIRKTQHS
130
TLSRKFVEVM
140
TEYNATQSKY
150
RDRCKDRIQR
160
QLEITGRTTT
170
NEELEDMLES
180
GKLAIFTDDI
190
KMDSQMTKQA
200
LNEIETRHNE
210
IIKLETSIRE
220
LHDMFVDMAM
230
LVESQGEMID
240
RIEYNVEHSV
250
DYVERAVSDT
260
KKAVKYQSKA
270
RRKKIMIIIC
280
CVVLGVVLAS
SIGGTLGL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0012505 | endomembrane system |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0031594 | neuromuscular junction |
| Cellular Component | GO:0005652 | nuclear lamina |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098793 | presynapse |
| Cellular Component | GO:0048787 | presynaptic active zone membrane |
| Cellular Component | GO:0042734 | presynaptic membrane |
| Cellular Component | GO:0031201 | SNARE complex |
| Molecular Function | GO:0019904 | protein domain specific binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0005102 | signaling receptor binding |
| Molecular Function | GO:0005484 | SNAP receptor activity |
| Molecular Function | GO:0000149 | SNARE binding |
| Biological Process | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter |
| Biological Process | GO:0006887 | exocytosis |
| Biological Process | GO:0006886 | intracellular protein transport |
| Biological Process | GO:1905302 | negative regulation of macropinocytosis |
| Biological Process | GO:0010977 | negative regulation of neuron projection development |
| Biological Process | GO:1903422 | negative regulation of synaptic vesicle recycling |
| Biological Process | GO:2000463 | positive regulation of excitatory postsynaptic potential |
| Biological Process | GO:0001956 | positive regulation of neurotransmitter secretion |
| Biological Process | GO:1904050 | positive regulation of spontaneous neurotransmitter secretion |
| Biological Process | GO:0072657 | protein localization to membrane |
| Biological Process | GO:0017157 | regulation of exocytosis |
| Biological Process | GO:0010468 | regulation of gene expression |
| Biological Process | GO:0060025 | regulation of synaptic activity |
| Biological Process | GO:0010807 | regulation of synaptic vesicle priming |
| Biological Process | GO:0061669 | spontaneous neurotransmitter secretion |
| Biological Process | GO:0016081 | synaptic vesicle docking |
| Biological Process | GO:0016079 | synaptic vesicle exocytosis |
| Biological Process | GO:0031629 | synaptic vesicle fusion to presynaptic active zone membrane |
| Biological Process | GO:0048278 | vesicle docking |
| Biological Process | GO:0006904 | vesicle docking involved in exocytosis |
| Biological Process | GO:0016192 | vesicle-mediated transport |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.