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Overview

Uniprot IDP61928
Protein NameLarge ribosomal subunit protein eL37
Gene NameRpl37
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
10 KGTSSFGKRRNKTHT
14 SFGKRRNKTHTLCRR
31 SKAYHLQKSTCGKCG
46 YPAKRKRKYNWSAKA
68 TGRMRHLKIVYRRFR

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MTKGTSSFGK 20 RRNKTHTLCR 30 RCGSKAYHLQ 40 KSTCGKCGYP 50 AKRKRKYNWS 60 AKAKRRNTTG 70 TGRMRHLKIV 80 YRRFRHGFRE 90 GTTPKPKRAA VAASSSS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0045202 synapse
Molecular Function GO:0019838 growth factor binding
Molecular Function GO:0097371 MDM2/MDM4 family protein binding
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0019843 rRNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Molecular Function GO:1990948 ubiquitin ligase inhibitor activity
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:1901798 positive regulation of signal transduction by p53 class mediator

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.