Search Results
Overview
| Uniprot ID | P62072 |
|---|---|
| Protein Name | Mitochondrial import inner membrane translocase subunit Tim10 |
| Gene Name | TIMM10 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 57 | CLDRCVSKYLDIHER |
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space
Protein Sequence
10
MDPLRAQQLA
20
AELEVEMMAD
30
MYNRMTSACH
40
RKCVPPHYKE
50
AELSKGESVC
60
LDRCVSKYLD
70
IHERMGKKLT
80
ELSMQDEELM
90
KRVQQSSGPA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005758 | mitochondrial intermembrane space |
| Cellular Component | GO:0042719 | mitochondrial intermembrane space chaperone complex |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0042721 | TIM22 mitochondrial import inner membrane insertion complex |
| Cellular Component | GO:0005744 | TIM23 mitochondrial import inner membrane translocase complex |
| Molecular Function | GO:0032977 | membrane insertase activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0051087 | protein-folding chaperone binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0045039 | protein insertion into mitochondrial inner membrane |
| Biological Process | GO:0006626 | protein targeting to mitochondrion |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0007605 | sensory perception of sound |
Reference
PMID: N/A