Search Results
Overview
| Uniprot ID | P62083 |
|---|---|
| Protein Name | Small ribosomal subunit protein eS7 |
| Gene Name | Rps7 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 147 | VGKRIRVKLDGSRLI |
| 155 | LDGSRLIKVHLDKAQ |
| 160 | LIKVHLDKAQQNNVE |
| 178 | ETFSGVYKKLTGKDV |
| 74 | PQLKSFQKIQVRLVR |
Function
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for rRNA maturation. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome
Protein Sequence
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0022626 | cytosolic ribosome |
| Cellular Component | GO:0022627 | cytosolic small ribosomal subunit |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0032991 | protein-containing complex |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Cellular Component | GO:0032040 | small-subunit processome |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0003730 | mRNA 3'-UTR binding |
| Molecular Function | GO:0048027 | mRNA 5'-UTR binding |
| Molecular Function | GO:0008266 | poly(U) RNA binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Molecular Function | GO:1990948 | ubiquitin ligase inhibitor activity |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:2000059 | negative regulation of ubiquitin-dependent protein catabolic process |
| Biological Process | GO:0001843 | neural tube closure |
| Biological Process | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator |
| Biological Process | GO:0042274 | ribosomal small subunit biogenesis |
| Biological Process | GO:0006364 | rRNA processing |
| Biological Process | GO:0006412 | translation |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.