Overview
| Uniprot ID | P62242 |
|---|
| Protein Name | Small ribosomal subunit protein eS8 |
|---|
| Gene Name | Rps8 |
|---|
| Organism | Mus musculus |
|---|
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 128 |
LGRKKGAKLTPEEEE |
Function
Component of the small ribosomal subunit (PubMed:36517592). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity)
Protein Sequence
10
MGISRDNWHK
20
RRKTGGKRKP
30
YHKKRKYELG
40
RPAANTKIGP
50
RRIHTVRVRG
60
GNKKYRALRL
70
DVGNFSWGSE
80
CCTRKTRIID
90
VVYNASNNEL
100
VRTKTLVKNC
110
IVLIDSTPYR
120
QWYESHYALP
130
LGRKKGAKLT
140
PEEEEILNKK
150
RSKKIQKKYD
160
ERKKNAKISS
170
LLEEQFQQGK
180
LLACIASRPG
190
QCGRADGYVL
200
EGKELEFYLR
KIKARKGK
Gene Ontology
| Classification |
GO ID |
Description |
| Biological Process |
GO:0042274 |
ribosomal small subunit biogenesis |
| Cellular Component |
GO:0005737 |
cytoplasm |
| Cellular Component |
GO:0005829 |
cytosol |
| Cellular Component |
GO:0022626 |
cytosolic ribosome |
| Cellular Component |
GO:0022627 |
cytosolic small ribosomal subunit |
| Cellular Component |
GO:0005783 |
endoplasmic reticulum |
| Cellular Component |
GO:0016020 |
membrane |
| Cellular Component |
GO:1990904 |
ribonucleoprotein complex |
| Cellular Component |
GO:0032040 |
small-subunit processome |
| Molecular Function |
GO:0003735 |
structural constituent of ribosome |
| Biological Process |
GO:0002181 |
cytoplasmic translation |
| Biological Process |
GO:0000462 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.