Overview
| Uniprot ID | P62250 |
|---|
| Protein Name | Small ribosomal subunit protein uS9 |
|---|
| Gene Name | Rps16 |
|---|
| Organism | Rattus norvegicus |
|---|
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 131 |
PRRCESKKFGGPGAR |
| 4 |
****MPSKGPLQSVQ |
| 60 |
EPVLLLGKERFAGVD |
| 98 |
ALVAYYQKYVDEASK |
Function
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome
Protein Sequence
10
MPSKGPLQSV
20
QVFGRKKTAT
30
AVAHCKRGNG
40
LIKVNGRPLE
50
MIEPRTLQYK
60
LLEPVLLLGK
70
ERFAGVDIRV
80
RVKGGGHVAQ
90
IYAIRQSISK
100
ALVAYYQKYV
110
DEASKKEIKD
120
ILIQYDRTLL
130
VADPRRCESK
140
KFGGPGARAR
YQKSYR
Gene Ontology
| Classification |
GO ID |
Description |
| Cellular Component |
GO:0098556 |
cytoplasmic side of rough endoplasmic reticulum membrane |
| Cellular Component |
GO:0005829 |
cytosol |
| Cellular Component |
GO:0022626 |
cytosolic ribosome |
| Cellular Component |
GO:0022627 |
cytosolic small ribosomal subunit |
| Cellular Component |
GO:0005783 |
endoplasmic reticulum |
| Cellular Component |
GO:0015935 |
small ribosomal subunit |
| Cellular Component |
GO:0032040 |
small-subunit processome |
| Cellular Component |
GO:0045202 |
synapse |
| Molecular Function |
GO:0003723 |
RNA binding |
| Molecular Function |
GO:0003735 |
structural constituent of ribosome |
| Biological Process |
GO:1990830 |
cellular response to leukemia inhibitory factor |
| Biological Process |
GO:0097421 |
liver regeneration |
| Biological Process |
GO:0000462 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process |
GO:0042274 |
ribosomal small subunit biogenesis |
| Biological Process |
GO:0006364 |
rRNA processing |
| Biological Process |
GO:0006412 |
translation |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.