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Overview

Uniprot IDP62269
Protein NameSmall ribosomal subunit protein uS13
Gene NameRPS18
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
106 LANGLDNKLREDLER
34 AFAITAIKGVGRRYA
47 YAHVVLRKADIDLTK

Function

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MSLVIPEKFQ 20 HILRVLNTNI 30 DGRRKIAFAI 40 TAIKGVGRRY 50 AHVVLRKADI 60 DLTKRAGELT 70 EDEVERVITI 80 MQNPRQYKIP 90 DWFLNRQKDV 100 KDGKYSQVLA 110 NGLDNKLRED 120 LERLKKIRAH 130 RGLRHFWGLR 140 VRGQHTKTTG 150 RRGRTVGVSK KK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0022627 cytosolic small ribosomal subunit
Cellular Component GO:0070062 extracellular exosome
Cellular Component GO:0005925 focal adhesion
Cellular Component GO:0016020 membrane
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0014069 postsynaptic density
Cellular Component GO:0005840 ribosome
Cellular Component GO:0015935 small ribosomal subunit
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0019843 rRNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0006412 translation

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.