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Overview

Uniprot IDP62425
Protein NameLarge ribosomal subunit protein eL8
Gene NameRpl7a
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
125 AEKKAAGKGDVPTKR
20 APAPAVVKKQEAKKV

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MPKGKKAKGK 20 KVAPAPAVVK 30 KQEAKKVVNP 40 LFEKRPKNFG 50 IGQDIQPKRD 60 LTRFVKWPRY 70 IRLQRQRAIL 80 YKRLKVPPAI 90 NQFTQALDRQ 100 TATQLLKLAH 110 KYRPETKQEK 120 KQRLLARAEK 130 KAAGKGDVPT 140 KRPPVLRAGV 150 NTVTTLVENK 160 KAQLVVIAHD 170 VDPIELVVFL 180 PALCRKMGVP 190 YCIIKGKARL 200 GRLVHRKTCT 210 TVAFTQVNSE 220 DKGALAKLVE 230 AIRTNYNDRY 240 DEIRRHWGGN 250 VLGPKSVARI 260 AKLEKAKAKE LATKLG

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0016020 membrane
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005840 ribosome
Cellular Component GO:0045202 synapse
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:1904401 cellular response to Thyroid stimulating hormone
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0000470 maturation of LSU-rRNA

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.