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Overview

Uniprot IDP62718
Protein NameLarge ribosomal subunit protein eL20
Gene NameRpl18a
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
11 SGTLREYKVVGRCLP
136 VEEIAAGKCRRPAVK
143 KCRRPAVKQFHDSKI
149 VKQFHDSKIKFPLPH
2 ******MKASGTLRE
41 APNHVVAKSRFWYFV
76 EKSPLRVKNFGIWLR

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MKASGTLREY 20 KVVGRCLPTP 30 KCHTPPLYRM 40 RIFAPNHVVA 50 KSRFWYFVSQ 60 LKKMKKSSGE 70 IVYCGQVFEK 80 SPLRVKNFGI 90 WLRYDSRSGT 100 HNMYREYRDL 110 TTAGAVTQCY 120 RDMGARHRAR 130 AHSIQIMKVE 140 EIAAGKCRRP 150 AVKQFHDSKI 160 KFPLPHRVLR 170 RQHKPRFTTK RPNTFF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0014069 postsynaptic density
Cellular Component GO:0005840 ribosome
Cellular Component GO:0045202 synapse
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0097327 response to antineoplastic agent

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.