Search Results
Overview
| Uniprot ID | P62762 |
|---|---|
| Protein Name | Visinin-like protein 1 |
| Gene Name | Vsnl1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 162 | FSKMDKNKDDQITLD |
| 36 | QWYKGFLKDCPSGRL |
| 7 | *MGKQNSKLAPEVME |
| 74 | HAFRTFDKNGDGTID |
Function
Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner
Protein Sequence
10
MGKQNSKLAP
20
EVMEDLVKST
30
EFNEHELKQW
40
YKGFLKDCPS
50
GRLNLEEFQQ
60
LYVKFFPYGD
70
ASKFAQHAFR
80
TFDKNGDGTI
90
DFREFICALS
100
ITSRGSFEQK
110
LNWAFNMYDL
120
DGDGKITRVE
130
MLEIIEAIYK
140
MVGTVIMMKM
150
NEDGLTPEQR
160
VDKIFSKMDK
170
NKDDQITLDE
180
FKEAAKSDPS
190
IVLLLQCDIQ
K
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Molecular Function | GO:0005509 | calcium ion binding |
| Biological Process | GO:0019722 | calcium-mediated signaling |
| Biological Process | GO:0007417 | central nervous system development |
| Biological Process | GO:0046676 | negative regulation of insulin secretion |
| Biological Process | GO:0045921 | positive regulation of exocytosis |
| Biological Process | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus |
| Biological Process | GO:0009966 | regulation of signal transduction |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.