Search Results
Overview
| Uniprot ID | P62824 |
|---|---|
| Protein Name | Ras-related protein Rab-3C |
| Gene Name | Rab3c |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 181 | AKDNINVKQTFERLV |
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion
Protein Sequence
10
MRHEAPMQMA
20
SAQDARFGQK
30
DSSDQNFDYM
40
FKLLIIGNSS
50
VGKTSFLFRY
60
ADDSFTSAFV
70
STVGIDFKVK
80
TVFKNEKRIK
90
LQIWDTAGQE
100
RYRTITTAYY
110
RGAMGFILMY
120
DITNEESFNA
130
VQDWSTQIKT
140
YSWDNAQVIL
150
AGNKCDMEDE
160
RVVSTERGQR
170
LGEQLGFEFF
180
ETSAKDNINV
190
KQTFERLVDI
200
ICDKMSESLE
210
TDPAITAAKQ
220
STRLKETPPP
PQPNCGC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005768 | endosome |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0008021 | synaptic vesicle |
| Cellular Component | GO:0030672 | synaptic vesicle membrane |
| Cellular Component | GO:0031982 | vesicle |
| Molecular Function | GO:0003925 | G protein activity |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0030742 | GTP-dependent protein binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0031489 | myosin V binding |
| Biological Process | GO:0019882 | antigen processing and presentation |
| Biological Process | GO:0006887 | exocytosis |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0017157 | regulation of exocytosis |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.