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Overview

Uniprot IDP62831
Protein NameLarge ribosomal subunit protein uL14
Gene NameRPL23
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
113 VNNKGEMKGSAITGP
123 AITGPVAKECADLWP
13 RGGSSGAKFRISLGL
43 NLYIISVKGIKGRLN
75 GKPELRKKVHPAVVI

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MSKRGRGGSS 20 GAKFRISLGL 30 PVGAVINCAD 40 NTGAKNLYII 50 SVKGIKGRLN 60 RLPAAGVGDM 70 VMATVKKGKP 80 ELRKKVHPAV 90 VIRQRKSYRR 100 KDGVFLYFED 110 NAGVIVNNKG 120 EMKGSAITGP 130 VAKECADLWP 140 RIASNAGSIA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0015934 large ribosomal subunit
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005654 nucleoplasm
Molecular Function GO:0070180 large ribosomal subunit rRNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Molecular Function GO:0001223 transcription coactivator binding
Molecular Function GO:1990948 ubiquitin ligase inhibitor activity
Molecular Function GO:0031625 ubiquitin protein ligase binding
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:1901798 positive regulation of signal transduction by p53 class mediator
Biological Process GO:0050821 protein stabilization
Biological Process GO:0032986 protein-DNA complex disassembly
Biological Process GO:0006412 translation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.