Search Results
Overview
| Uniprot ID | P62832 |
|---|---|
| Protein Name | Large ribosomal subunit protein uL14 |
| Gene Name | Rpl23 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 113 | VNNKGEMKGSAITGP |
| 43 | NLYIISVKGIKGRLN |
| 66 | DMVMATVKKGKPELR |
| 75 | GKPELRKKVHPAVVI |
Function
Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell
Protein Sequence
10
MSKRGRGGSS
20
GAKFRISLGL
30
PVGAVINCAD
40
NTGAKNLYII
50
SVKGIKGRLN
60
RLPAAGVGDM
70
VMATVKKGKP
80
ELRKKVHPAV
90
VIRQRKSYRR
100
KDGVFLYFED
110
NAGVIVNNKG
120
EMKGSAITGP
130
VAKECADLWP
140
RIASNAGSIA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0098556 | cytoplasmic side of rough endoplasmic reticulum membrane |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0022625 | cytosolic large ribosomal subunit |
| Cellular Component | GO:0022626 | cytosolic ribosome |
| Cellular Component | GO:0015934 | large ribosomal subunit |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0032991 | protein-containing complex |
| Cellular Component | GO:0005840 | ribosome |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0070180 | large ribosomal subunit rRNA binding |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Molecular Function | GO:0001223 | transcription coactivator binding |
| Molecular Function | GO:1990948 | ubiquitin ligase inhibitor activity |
| Molecular Function | GO:0031625 | ubiquitin protein ligase binding |
| Biological Process | GO:0002181 | cytoplasmic translation |
| Biological Process | GO:0070314 | G1 to G0 transition |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:2000059 | negative regulation of ubiquitin-dependent protein catabolic process |
| Biological Process | GO:0008284 | positive regulation of cell population proliferation |
| Biological Process | GO:1901798 | positive regulation of signal transduction by p53 class mediator |
| Biological Process | GO:0050821 | protein stabilization |
| Biological Process | GO:0032986 | protein-DNA complex disassembly |
| Biological Process | GO:1903450 | regulation of G1 to G0 transition |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.