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Overview

Uniprot IDP62841
Protein NameSmall ribosomal subunit protein uS19
Gene NameRPS15
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
52 LNRGLRRKQHSLLKR
77 MEKPEVVKTHLRDMI

Function

Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399)

Protein Sequence

10 MAEVEQKKKR 20 TFRKFTYRGV 30 DLDQLLDMSY 40 EQLMQLYSAR 50 QRRRLNRGLR 60 RKQHSLLKRL 70 RKAKKEAPPM 80 EKPEVVKTHL 90 RDMIILPEMV 100 GSMVGVYNGK 110 TFNQVEIKPE 120 MIGHYLGEFS 130 ITYKPVKHGR 140 PGIGATHSSR FIPLK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0097371 MDM2/MDM4 family protein binding
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Molecular Function GO:1990948 ubiquitin ligase inhibitor activity
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0097421 liver regeneration
Biological Process GO:0001649 osteoblast differentiation
Biological Process GO:1901798 positive regulation of signal transduction by p53 class mediator
Biological Process GO:0000028 ribosomal small subunit assembly
Biological Process GO:0042274 ribosomal small subunit biogenesis
Biological Process GO:0000056 ribosomal small subunit export from nucleus
Biological Process GO:0006364 rRNA processing
Biological Process GO:0006412 translation
Cellular Component GO:0005829 cytosol
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0022627 cytosolic small ribosomal subunit
Cellular Component GO:0005925 focal adhesion
Cellular Component GO:0016020 membrane
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0045202 synapse

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.