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Overview

Uniprot IDP62845
Protein NameSmall ribosomal subunit protein uS19
Gene NameRps15
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
52 LNRGLRRKQHSLLKR
77 MEKPEVVKTHLRDMI

Function

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MAEVEQKKKR 20 TFRKFTYRGV 30 DLDQLLDMSY 40 EQLMQLYSAR 50 QRRRLNRGLR 60 RKQHSLLKRL 70 RKAKKEAPPM 80 EKPEVVKTHL 90 RDMIILPEMV 100 GSMVGVYNGK 110 TFNQVEIKPE 120 MIGHYLGEFS 130 ITYKPVKHGR 140 PGIGATHSSR FIPLK

Gene Ontology

Classification GO ID Description
Molecular Function GO:0003723 RNA binding
Cellular Component GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0022627 cytosolic small ribosomal subunit
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0098794 postsynapse
Cellular Component GO:0005840 ribosome
Cellular Component GO:0045202 synapse
Molecular Function GO:0097371 MDM2/MDM4 family protein binding
Molecular Function GO:0003735 structural constituent of ribosome
Molecular Function GO:1990948 ubiquitin ligase inhibitor activity
Biological Process GO:0097421 liver regeneration
Biological Process GO:1901798 positive regulation of signal transduction by p53 class mediator
Biological Process GO:0000028 ribosomal small subunit assembly
Biological Process GO:0042274 ribosomal small subunit biogenesis
Biological Process GO:0000056 ribosomal small subunit export from nucleus
Biological Process GO:0006364 rRNA processing
Biological Process GO:0006412 translation

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.