Search Results

Overview

Uniprot IDP62897
Protein NameCytochrome c, somatic
Gene NameCycs
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
28 VEKGGKHKTGPNLHG
40 LHGLFGRKTGQAAGF
54 FSYTDANKNKGITWG
74 EYLENPKKYIPGTKM
87 KMIFAGIKKKGERAD

Function

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain

Protein Sequence

10 MGDVEKGKKI 20 FVQKCAQCHT 30 VEKGGKHKTG 40 PNLHGLFGRK 50 TGQAAGFSYT 60 DANKNKGITW 70 GEDTLMEYLE 80 NPKKYIPGTK 90 MIFAGIKKKG 100 ERADLIAYLK KATNE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0043293 apoptosome
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005758 mitochondrial intermembrane space
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0043209 myelin sheath
Cellular Component GO:0005634 nucleus
Molecular Function GO:0009055 electron transfer activity
Molecular Function GO:0019899 enzyme binding
Molecular Function GO:0020037 heme binding
Molecular Function GO:0046872 metal ion binding
Biological Process GO:0006915 apoptotic process
Biological Process GO:0042743 hydrogen peroxide metabolic process
Biological Process GO:0097193 intrinsic apoptotic signaling pathway
Biological Process GO:0006123 mitochondrial electron transport, cytochrome c to oxygen
Biological Process GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c

Reference

[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.

[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.