Search Results
Overview
| Uniprot ID | P63029 |
|---|---|
| Protein Name | Translationally-controlled tumor protein |
| Gene Name | Tpt1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 102 | YMKSLKGKLEEQKPE |
| 107 | KGKLEEQKPERVKPF |
Function
Involved in calcium binding and microtubule stabilization (By similarity). Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein (By similarity)
Protein Sequence
10
MIIYRDLISH
20
DELFSDIYKI
30
REIADGLCLE
40
VEGKMVSRTE
50
GAIDDSLIGG
60
NASAEGPEGE
70
GTESTVVTGV
80
DIVMNHHLQE
90
TSFTKEAYKK
100
YIKDYMKSLK
110
GKLEEQKPER
120
VKPFMTGAAE
130
QIKHILANFN
140
NYQFFIGENM
150
NPDGMVALLD
160
YREDGVTPFM
170
IFFKDGLEME
KC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0140297 | DNA-binding transcription factor binding |
| Biological Process | GO:2000384 | negative regulation of ectoderm development |
| Biological Process | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage |
| Biological Process | GO:0009615 | response to virus |
| Biological Process | GO:0007283 | spermatogenesis |
| Biological Process | GO:0019827 | stem cell population maintenance |
| Cellular Component | GO:0005881 | cytoplasmic microtubule |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0005771 | multivesicular body |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0000922 | spindle pole |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.