Search Results
Overview
| Uniprot ID | P63100 |
|---|---|
| Protein Name | Calcineurin subunit B type 1 |
| Gene Name | Ppp3r1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 142 | KTIINADKDGDGRIS |
| 85 | GVSQFSVKGDKEQKL |
Function
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity
Protein Sequence
10
MGNEASYPLE
20
MCSHFDADEI
30
KRLGKRFKKL
40
DLDNSGSLSV
50
EEFMSLPELQ
60
QNPLVQRVID
70
IFDTDGNGEV
80
DFKEFIEGVS
90
QFSVKGDKEQ
100
KLRFAFRIYD
110
MDKDGYISNG
120
ELFQVLKMMV
130
GNNLKDTQLQ
140
QIVDKTIINA
150
DKDGDGRISF
160
EEFCAVVGGL
170
DIHKKMVVDV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005955 | calcineurin complex |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0042383 | sarcolemma |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity |
| Molecular Function | GO:0019902 | phosphatase binding |
| Biological Process | GO:0033173 | calcineurin-NFAT signaling cascade |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.