Search Results

Overview

Uniprot IDP63267
Protein NameActin, gamma-enteric smooth muscle
Gene NameACTG2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
114 TEAPLNPKANREKMT
192 DLTDYLMKILTERGY
329 APSTMKIKIIAPPER
51 VMVGMGQKDSYVGDE
62 VGDEAQSKRGILTLK
69 KRGILTLKYPIEHGI

Function

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells

Protein Sequence

10 MCEEETTALV 20 CDNGSGLCKA 30 GFAGDDAPRA 40 VFPSIVGRPR 50 HQGVMVGMGQ 60 KDSYVGDEAQ 70 SKRGILTLKY 80 PIEHGIITNW 90 DDMEKIWHHS 100 FYNELRVAPE 110 EHPTLLTEAP 120 LNPKANREKM 130 TQIMFETFNV 140 PAMYVAIQAV 150 LSLYASGRTT 160 GIVLDSGDGV 170 THNVPIYEGY 180 ALPHAIMRLD 190 LAGRDLTDYL 200 MKILTERGYS 210 FVTTAEREIV 220 RDIKEKLCYV 230 ALDFENEMAT 240 AASSSSLEKS 250 YELPDGQVIT 260 IGNERFRCPE 270 TLFQPSFIGM 280 ESAGIHETTY 290 NSIMKCDIDI 300 RKDLYANNVL 310 SGGTTMYPGI 320 ADRMQKEITA 330 LAPSTMKIKI 340 IAPPERKYSV 350 WIGGSILASL 360 STFQQMWISK 370 PEYDEAGPSI VHRKCF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0072562 blood microparticle
Cellular Component GO:0044297 cell body
Cellular Component GO:0071944 cell periphery
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0070062 extracellular exosome
Cellular Component GO:0005615 extracellular space
Cellular Component GO:0030175 filopodium
Cellular Component GO:0030027 lamellipodium
Cellular Component GO:0032982 myosin filament
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016787 hydrolase activity
Molecular Function GO:0005200 structural constituent of cytoskeleton
Biological Process GO:1905641 cellular response to acetaldehyde
Biological Process GO:0071354 cellular response to interleukin-6
Biological Process GO:0090131 mesenchyme migration
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0045471 response to ethanol

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[2] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.