Search Results

Overview

Uniprot IDP68134
Protein NameActin, alpha skeletal muscle
Gene NameActa1
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
115 TEAPLNPKANREKMT
293 KCDIDIRKDLYANNV
317 GIADRMQKEITALAP
330 APSTMKIKIIAPPER
52 VMVGMGQKDSYVGDE
63 VGDEAQSKRGILTLK
70 KRGILTLKYPIEHGI

Function

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells

Protein Sequence

10 MCDEDETTAL 20 VCDNGSGLVK 30 AGFAGDDAPR 40 AVFPSIVGRP 50 RHQGVMVGMG 60 QKDSYVGDEA 70 QSKRGILTLK 80 YPIEHGIITN 90 WDDMEKIWHH 100 TFYNELRVAP 110 EEHPTLLTEA 120 PLNPKANREK 130 MTQIMFETFN 140 VPAMYVAIQA 150 VLSLYASGRT 160 TGIVLDSGDG 170 VTHNVPIYEG 180 YALPHAIMRL 190 DLAGRDLTDY 200 LMKILTERGY 210 SFVTTAEREI 220 VRDIKEKLCY 230 VALDFENEMA 240 TAASSSSLEK 250 SYELPDGQVI 260 TIGNERFRCP 270 ETLFQPSFIG 280 MESAGIHETT 290 YNSIMKCDID 300 IRKDLYANNV 310 MSGGTTMYPG 320 IADRMQKEIT 330 ALAPSTMKIK 340 IIAPPERKYS 350 VWIGGSILAS 360 LSTFQQMWIT 370 KQEYDEAGPS IVHRKCF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0005884 actin filament
Cellular Component GO:0044297 cell body
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0030175 filopodium
Cellular Component GO:0030027 lamellipodium
Cellular Component GO:0032991 protein-containing complex
Cellular Component GO:0030017 sarcomere
Cellular Component GO:0001725 stress fiber
Cellular Component GO:0005865 striated muscle thin filament
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016787 hydrolase activity
Molecular Function GO:0005200 structural constituent of cytoskeleton
Biological Process GO:0090131 mesenchyme migration
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0048741 skeletal muscle fiber development
Biological Process GO:0030240 skeletal muscle thin filament assembly

Reference

[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.