Search Results

Overview

Uniprot IDP69682
Protein NameAdaptin ear-binding coat-associated protein 1
Gene NameNecap1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
148 QEMDSRPKLDLGFKE
154 PKLDLGFKEGQTIKL
169 SIGNITAKKGGTSKP

Function

Involved in endocytosis

Protein Sequence

10 MAAELEYESV 20 LCVKPDVSVY 30 RIPPRASNRG 40 YRASDWKLDQ 50 PDWTGRLRIT 60 SKGKIAYIKL 70 EDKVSGELFA 80 QAPVEQYPGI 90 AVETVADSSR 100 YFVIRIQDGT 110 GRSAFIGIGF 120 TDRGDAFDFN 130 VSLQDHFKWV 140 KQETEISKES 150 QEMDSRPKLD 160 LGFKEGQTIK 170 LSIGNITAKK 180 GGTSKPRASG 190 TGGLSLLPPP 200 PGGKVTIPPP 210 SSSVAISNHV 220 TPPPIPKSNH 230 GSNDSDILLD 240 LDSPAPVPTS 250 APAPAPASTS 260 NDLWGDFSTA 270 SSSVPNQAPQ PSNWVQF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030125 clathrin vesicle coat
Cellular Component GO:0005905 clathrin-coated pit
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0098793 presynapse
Biological Process GO:0006897 endocytosis
Biological Process GO:0140238 presynaptic endocytosis
Biological Process GO:0015031 protein transport
Biological Process GO:0016192 vesicle-mediated transport

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.