Search Results
Overview
| Uniprot ID | P69891 |
|---|---|
| Protein Name | Hemoglobin subunit gamma-1 |
| Gene Name | HBG1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 67 | KVKAHGKKVLTSLGD |
| 77 | TSLGDATKHLDDLKG |
| 83 | TKHLDDLKGTFAQLS |
| 96 | LSELHCDKLHVDPEN |
Function
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains
Protein Sequence
10
MGHFTEEDKA
20
TITSLWGKVN
30
VEDAGGETLG
40
RLLVVYPWTQ
50
RFFDSFGNLS
60
SASAIMGNPK
70
VKAHGKKVLT
80
SLGDATKHLD
90
DLKGTFAQLS
100
ELHCDKLHVD
110
PENFKLLGNV
120
LVTVLAIHFG
130
KEFTPEVQAS
140
WQKMVTAVAS
ALSSRYH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0031838 | haptoglobin-hemoglobin complex |
| Cellular Component | GO:0005833 | hemoglobin complex |
| Molecular Function | GO:0020037 | heme binding |
| Molecular Function | GO:0031721 | hemoglobin alpha binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0019825 | oxygen binding |
| Molecular Function | GO:0005344 | oxygen carrier activity |
| Biological Process | GO:0015670 | carbon dioxide transport |
| Biological Process | GO:0048821 | erythrocyte development |
| Biological Process | GO:0015671 | oxygen transport |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.