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Overview

Uniprot IDP69892
Protein NameHemoglobin subunit gamma-2
Gene NameHBG2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
83 IKHLDDLKGTFAQLS

Function

Gamma chains make up the fetal hemoglobin F, in combination with alpha chains

Protein Sequence

10 MGHFTEEDKA 20 TITSLWGKVN 30 VEDAGGETLG 40 RLLVVYPWTQ 50 RFFDSFGNLS 60 SASAIMGNPK 70 VKAHGKKVLT 80 SLGDAIKHLD 90 DLKGTFAQLS 100 ELHCDKLHVD 110 PENFKLLGNV 120 LVTVLAIHFG 130 KEFTPEVQAS 140 WQKMVTGVAS ALSSRYH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0072562 blood microparticle
Cellular Component GO:0005829 cytosol
Cellular Component GO:0031838 haptoglobin-hemoglobin complex
Cellular Component GO:0005833 hemoglobin complex
Molecular Function GO:0020037 heme binding
Molecular Function GO:0031721 hemoglobin alpha binding
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0019825 oxygen binding
Molecular Function GO:0005344 oxygen carrier activity
Biological Process GO:0015670 carbon dioxide transport
Biological Process GO:0048821 erythrocyte development
Biological Process GO:0015671 oxygen transport

Reference

[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.