Search Results

Overview

Uniprot IDP78332
Protein NameRNA-binding protein 6
Gene NameRBM6
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
1019 RGNDRREKLQSFDSP
1066 QQATGWRKGTGLGYG
331 RPAFGIQKGEFEHSE
36 DYPPPPLKSHAQERH
425 MFGYGQSKSFPEGKT
580 ITYPQPQKTSIPAPL
759 HMHYYQGKKYFRDRR
879 APAEDVFKKPLPPTV
880 PAEDVFKKPLPPTVK

Function

Specifically binds poly(G) RNA homopolymers in vitro

Protein Sequence

10 MWGDSRPANR 20 TGPFRGSQEE 30 RFAPGWNRDY 40 PPPPLKSHAQ 50 ERHSGNFPGR 60 DSLPFDFQGH 70 SGPPFANVEE 80 HSFSYGARDG 90 PHGDYRGGEG 100 PGHDFRGGDF 110 SSSDFQSRDS 120 SQLDFRGRDI 130 HSGDFRDREG 140 PPMDYRGGDG 150 TSMDYRGREA 160 PHMNYRDRDA 170 HAVDFRGRDA 180 PPSDFRGRGT 190 YDLDFRGRDG 200 SHADFRGRDL 210 SDLDFRAREQ 220 SRSDFRNRDV 230 SDLDFRDKDG 240 TQVDFRGRGS 250 GTTDLDFRDR 260 DTPHSDFRGR 270 HRSRTDQDFR 280 GREMGSCMEF 290 KDREMPPVDP 300 NILDYIQPST 310 QDREHSGMNV 320 NRREESTHDH 330 TIERPAFGIQ 340 KGEFEHSETR 350 EGETQGVAFE 360 HESPADFQNS 370 QSPVQDQDKS 380 QLSGREEQSS 390 DAGLFKEEGG 400 LDFLGRQDTD 410 YRSMEYRDVD 420 HRLPGSQMFG 430 YGQSKSFPEG 440 KTARDAQRDL 450 QDQDYRTGPS 460 EEKPSRLIRL 470 SGVPEDATKE 480 EILNAFRTPD 490 GMPVKNLQLK 500 EYNTGYDYGY 510 VCVEFSLLED 520 AIGCMEANQG 530 TLMIQDKEVT 540 LEYVSSLDFW 550 YCKRCKANIG 560 GHRSSCSFCK 570 NPREVTEAKQ 580 ELITYPQPQK 590 TSIPAPLEKQ 600 PNQPLRPADK 610 EPEPRKREEG 620 QESRLGHQKR 630 EAERYLPPSR 640 REGPTFRRDR 650 ERESWSGETR 660 QDGESKTIML 670 KRIYRSTPPE 680 VIVEVLEPYV 690 RLTTANVRII 700 KNRTGPMGHT 710 YGFIDLDSHA 720 EALRVVKILQ 730 NLDPPFSIDG 740 KMVAVNLATG 750 KRRNDSGDHS 760 DHMHYYQGKK 770 YFRDRRGGGR 780 NSDWSSDTNR 790 QGQQSSSDCY 800 IYDSATGYYY 810 DPLAGTYYDP 820 NTQQEVYVPQ 830 DPGLPEEEEI 840 KEKKPTSQGK 850 SSSKKEMSKR 860 DGKEKKDRGV 870 TRFQENASEG 880 KAPAEDVFKK 890 PLPPTVKKEE 900 SPPPPKVVNP 910 LIGLLGEYGG 920 DSDYEEEEEE 930 EQTPPPQPRT 940 AQPQKREEQT 950 KKENEEDKLT 960 DWNKLACLLC 970 RRQFPNKEVL 980 IKHQQLSDLH 990 KQNLEIHRKI 1000 KQSEQELAYL 1010 ERREREGKFK 1020 GRGNDRREKL 1030 QSFDSPERKR 1040 IKYSRETDSD 1050 RKLVDKEDID 1060 TSSKGGCVQQ 1070 ATGWRKGTGL 1080 GYGHPGLASS 1090 EEAEGRMRGP 1100 SVGASGRTSK 1110 RQSNETYRDA 1120 VRRVMFARYK ELD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0003723 RNA binding
Biological Process GO:0000398 mRNA splicing, via spliceosome
Biological Process GO:0006396 RNA processing

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.