Search Results
Overview
| Uniprot ID | P78406 |
|---|---|
| Protein Name | mRNA export factor RAE1 |
| Gene Name | RAE1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 350 | EFYNPQKKNYIFLRN |
Function
Acts as a mRNA export factor involved in nucleocytoplasmic transport (PubMed:20498086, PubMed:33849972). Plays a role in mitotic bipolar spindle formation (PubMed:17172455). May function in attaching cytoplasmic mRNPs to the cytoskeleton both directly or indirectly (PubMed:17172455)
Protein Sequence
10
MSLFGTTSGF
20
GTSGTSMFGS
30
ATTDNHNPMK
40
DIEVTSSPDD
50
SIGCLSFSPP
60
TLPGNFLIAG
70
SWANDVRCWE
80
VQDSGQTIPK
90
AQQMHTGPVL
100
DVCWSDDGSK
110
VFTASCDKTA
120
KMWDLSSNQA
130
IQIAQHDAPV
140
KTIHWIKAPN
150
YSCVMTGSWD
160
KTLKFWDTRS
170
SNPMMVLQLP
180
ERCYCADVIY
190
PMAVVATAER
200
GLIVYQLENQ
210
PSEFRRIESP
220
LKHQHRCVAI
230
FKDKQNKPTG
240
FALGSIEGRV
250
AIHYINPPNP
260
AKDNFTFKCH
270
RSNGTNTSAP
280
QDIYAVNGIA
290
FHPVHGTLAT
300
VGSDGRFSFW
310
DKDARTKLKT
320
SEQLDQPISA
330
CCFNHNGNIF
340
AYASSYDWSK
350
GHEFYNPQKK
360
NYIFLRNAAE
ELKPRNKK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0001650 | fibrillar center |
| Cellular Component | GO:0097431 | mitotic spindle pole |
| Cellular Component | GO:0005635 | nuclear envelope |
| Cellular Component | GO:0005643 | nuclear pore |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0008017 | microtubule binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0043130 | ubiquitin binding |
| Biological Process | GO:0051301 | cell division |
| Biological Process | GO:0006406 | mRNA export from nucleus |
| Biological Process | GO:0006913 | nucleocytoplasmic transport |
| Biological Process | GO:0060236 | regulation of mitotic spindle organization |
| Biological Process | GO:0006405 | RNA export from nucleus |
| Biological Process | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.