Search Results
Overview
| Uniprot ID | P79379 |
|---|---|
| Protein Name | Metallothionein-2A |
| Gene Name | MT2A |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 31 | CKCTSCKKSCCSCCP |
| 51 | CAQGCICKGASDKCS |
Function
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids
Protein Sequence
10
MDPNCSCAAG
20
GSCTCAGSCK
30
CKDCKCTSCK
40
KSCCSCCPVG
50
CAKCAQGCIC
60
KGASDKCSCC
A
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0071276 | cellular response to cadmium ion |
| Biological Process | GO:0071280 | cellular response to copper ion |
| Biological Process | GO:0036018 | cellular response to erythropoietin |
| Biological Process | GO:0071294 | cellular response to zinc ion |
| Biological Process | GO:0010273 | detoxification of copper ion |
| Biological Process | GO:0006882 | intracellular zinc ion homeostasis |
| Biological Process | GO:0045926 | negative regulation of growth |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.