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Overview

Uniprot IDP79431
Protein NameMetallothionein-1E
Gene NameMT1E
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
31 CRCTSCKKSCCSCCP
51 CAQGCICKGASDKCS

Function

Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids

Protein Sequence

10 MDPNCSCPTG 20 GSCSCAGSCT 30 CKACRCTSCK 40 KSCCSCCPVG 50 CAKCAQGCIC 60 KGASDKCSCC A

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0071276 cellular response to cadmium ion
Biological Process GO:0071280 cellular response to copper ion
Biological Process GO:0071294 cellular response to zinc ion
Biological Process GO:0010273 detoxification of copper ion
Biological Process GO:0006882 intracellular zinc ion homeostasis
Biological Process GO:0045926 negative regulation of growth

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.