Search Results
Overview
| Uniprot ID | P81045 |
|---|---|
| Protein Name | Cytochrome c oxidase copper chaperone |
| Gene Name | COX17 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 39 | RDACIIEKGEEHCGH |
Function
Copper metallochaperone involved in the assembly of cytochrome c oxidase (respiratory chain complex IV, CIV). Binds two copper ions and delivers them to the metallochaperones SCO1 and SCO2, which co-chaperone the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2)
Protein Sequence
10
PGLAAAIPAP
20
PESQEKKPLK
30
PCCACPETKK
40
ARDACIIEKG
50
EEHCGHLIEA
60
HKECMRALGF
KI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005758 | mitochondrial intermembrane space |
| Molecular Function | GO:0016531 | copper chaperone activity |
| Molecular Function | GO:0005507 | copper ion binding |
| Biological Process | GO:0033617 | mitochondrial respiratory chain complex IV assembly |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.