Search Results
Overview
| Uniprot ID | P81133 |
|---|---|
| Protein Name | Single-minded homolog 1 |
| Gene Name | SIM1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 379 | KSRLSSSKSKSRTSP |
| 381 | RLSSSKSKSRTSPYP |
Function
Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult
Protein Sequence
10
MKEKSKNAAR
20
TRREKENSEF
30
YELAKLLPLP
40
SAITSQLDKA
50
SIIRLTTSYL
60
KMRVVFPEGL
70
GEAWGHSSRT
80
SPLDNVGREL
90
GSHLLQTLDG
100
FIFVVAPDGK
110
IMYISETASV
120
HLGLSQVELT
130
GNSIYEYIHP
140
ADHDEMTAVL
150
TAHQPYHSHF
160
VQEYEIERSF
170
FLRMKCVLAK
180
RNAGLTCGGY
190
KVIHCSGYLK
200
IRQYSLDMSP
210
FDGCYQNVGL
220
VAVGHSLPPS
230
AVTEIKLHSN
240
MFMFRASLDM
250
KLIFLDSRVA
260
ELTGYEPQDL
270
IEKTLYHHVH
280
GCDTFHLRCA
290
HHLLLVKGQV
300
TTKYYRFLAK
310
HGGWVWVQSY
320
ATIVHNSRSS
330
RPHCIVSVNY
340
VLTDTEYKGL
350
QLSLDQISAS
360
KPAFSYTSSS
370
TPTMTDNRKG
380
AKSRLSSSKS
390
KSRTSPYPQY
400
SGFHTERSES
410
DHDSQWGGSP
420
LTDTASPQLL
430
DPADRPGSQH
440
DASCAYRQFS
450
DRSSLCYGFA
460
LDHSRLVEER
470
HFHTQACEGG
480
RCEAGRYFLG
490
TPQAGREPWW
500
GSRAALPLTK
510
ASPESREAYE
520
NSMPHIASVH
530
RIHGRGHWDE
540
DSVVSSPDPG
550
SASESGDRYR
560
TEQYQSSPHE
570
PSKIETLIRA
580
TQQMIKEEEN
590
RLQLRKAPSD
600
QLASINGAGK
610
KHSLCFANYQ
620
QPPPTGEVCH
630
GSALANTSPC
640
DHIQQREGKM
650
LSPHENDYDN
660
SPTALSRISS
670
PNSDRISKSS
680
LILAKDYLHS
690
DISPHQTAGD
700
HPTVSPNCFG
710
SHRQYFDKHA
720
YTLTGYALEH
730
LYDSETIRNY
740
SLGCNGSHFD
750
VTSHLRMQPD
760
PAQGHKGTSV
IITNGS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0007399 | nervous system development |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
| Biological Process | GO:0001657 | ureteric bud development |
Reference
[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.