Search Results
Overview
| Uniprot ID | P82909 |
|---|---|
| Protein Name | Alpha-ketoglutarate dehydrogenase component 4 |
| Gene Name | KGD4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 87 | LPQKYRRKLVSQEEM |
Function
Molecular adapter that is necessary to form a stable 2-oxoglutarate dehydrogenase enzyme complex (OGDHC). Enables the specific recruitment of E3 subunit to E2 subunit in the 2-oxoglutarate dehydrogenase complex (OGDHC)
Protein Sequence
10
MMGSKMASAS
20
RVVQVVKPHT
30
PLIRFPDRRD
40
NPKPNVSEAL
50
RSAGLPSHSS
60
VISQHSKGSK
70
SPDLLMYQGP
80
PDTAEIIKTL
90
PQKYRRKLVS
100
QEEMEFIQRG
GPE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0045252 | oxoglutarate dehydrogenase complex |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Biological Process | GO:0006103 | 2-oxoglutarate metabolic process |
| Biological Process | GO:0006099 | tricarboxylic acid cycle |
Reference
[1] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.