Search Results
Overview
| Uniprot ID | P83105 |
|---|---|
| Protein Name | Serine protease HTRA4 |
| Gene Name | HTRA4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 241 | ARYEAVVKDIDLKLD |
Function
Serine protease
Protein Sequence
10
MIRPQLRTAG
20
LGRCLLPGLL
30
LLLVPVLWAG
40
AEKLHTQPSC
50
PAVCQPTRCP
60
ALPTCALGTT
70
PVFDLCRCCR
80
VCPAAEREVC
90
GGAQGQPCAP
100
GLQCLQPLRP
110
GFPSTCGCPT
120
LGGAVCGSDR
130
RTYPSMCALR
140
AENRAARRLG
150
KVPAVPVQWG
160
NCGDTGTRSA
170
GPLRRNYNFI
180
AAVVEKVAPS
190
VVHVQLWGRL
200
LHGSRLVPVY
210
SGSGFIVSED
220
GLIITNAHVV
230
RNQQWIEVVL
240
QNGARYEAVV
250
KDIDLKLDLA
260
VIKIESNAEL
270
PVLMLGRSSD
280
LRAGEFVVAL
290
GSPFSLQNTA
300
TAGIVSTKQR
310
GGKELGMKDS
320
DMDYVQIDAT
330
INYGNSGGPL
340
VNLDGDVIGV
350
NSLRVTDGIS
360
FAIPSDRVRQ
370
FLAEYHEHQM
380
KGKAFSNKKY
390
LGLQMLSLTV
400
PLSEELKMHY
410
PDFPDVSSGV
420
YVCKVVEGTA
430
AQSSGLRDHD
440
VIVNINGKPI
450
TTTTDVVKAL
460
DSDSLSMAVL
470
RGKDNLLLTV
IPETIN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005576 | extracellular region |
| Molecular Function | GO:0004175 | endopeptidase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0004252 | serine-type endopeptidase activity |
| Biological Process | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process | GO:0043065 | positive regulation of apoptotic process |
| Biological Process | GO:0012501 | programmed cell death |
| Biological Process | GO:0006508 | proteolysis |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.