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Overview

Uniprot IDP83881
Protein NameLarge ribosomal subunit protein eL42
Gene NameRPL36A
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
97 HFELGGDKKRKGQVI

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MVNVPKTRRT 20 FCKKCGKHQP 30 HKVTQYKKGK 40 DSLYAQGKRR 50 YDRKQSGYGG 60 QTKPIFRKKA 70 KTTKKIVLRL 80 ECVEPNCRSK 90 RMLAIKRCKH 100 FELGGDKKRK GQVIQF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0005840 ribosome
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:1901740 negative regulation of myoblast fusion
Biological Process GO:0006941 striated muscle contraction
Biological Process GO:0006412 translation

Reference

[1] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.

[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.