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Overview

Uniprot IDP84100
Protein NameLarge ribosomal subunit protein eL19
Gene NameRpl19
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
126 MYHSLYLKVKGNVFK
128 HSLYLKVKGNVFKNK
133 KVKGNVFKNKRILME
144 ILMEHIHKLKADKAR
153 KADKARKKLLADQAE
186 AKKEEIIKTLSKEEE
190 EIIKTLSKEEETKK*
46 QQIRKLIKDGLIIRK
80 GRHMGIGKRKGTANA

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MSMLRLQKRL 20 ASSVLRCGKK 30 KVWLDPNETN 40 EIANANSRQQ 50 IRKLIKDGLI 60 IRKPVTVHSR 70 ARCRKNTLAR 80 RKGRHMGIGK 90 RKGTANARMP 100 EKVTWMRRMR 110 ILRRLLRRYR 120 ESKKIDRHMY 130 HSLYLKVKGN 140 VFKNKRILME 150 HIHKLKADKA 160 RKKLLADQAE 170 ARRSKTKEAR 180 KRREERLQAK 190 KEEIIKTLSK EEETKK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0045202 synapse
Molecular Function GO:1990932 5.8S rRNA binding
Molecular Function GO:0070180 large ribosomal subunit rRNA binding
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0097421 liver regeneration

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.