Search Results
Overview
| Uniprot ID | P84101 |
|---|---|
| Protein Name | Small EDRK-rich factor 2 |
| Gene Name | SERF2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 47 | DSEIMQQKQKKANEK |
Function
Positive regulator of amyloid protein aggregation and proteotoxicity (PubMed:20723760). Induces conformational changes in amyloid proteins, such as HTT, driving them into compact formations preceding the formation of aggregates (PubMed:20723760)
Protein Sequence
10
MTRGNQRELA
20
RQKNMKKQSD
30
SVKGKRRDDG
40
LSAAARKQRD
50
SEIMQQKQKK
ANEKKEEPK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Biological Process | GO:0031648 | protein destabilization |
Reference
PMID: N/A