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Overview

Uniprot IDP85969
Protein NameBeta-soluble NSF attachment protein
Gene NameNapb
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
19 QLMAEAEKRVKASHS
22 AEAEKRVKASHSFLR
56 ANMFKMAKNWSAAGN
93 VDAGNAYKKADPQEA

Function

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus

Protein Sequence

10 MDNAGKEREA 20 VQLMAEAEKR 30 VKASHSFLRG 40 LFGGNTRIEE 50 ACEMYTRAAN 60 MFKMAKNWSA 70 AGNAFCQAAK 80 LHMQLQSKHD 90 SATSFVDAGN 100 AYKKADPQEA 110 INCLNAAIDI 120 YTDMGRFTIA 130 AKHHITIAEI 140 YETELVDIEK 150 AIAHYEQSAD 160 YYKGEESNSA 170 NKCLLKVAAY 180 AAQLEQYQKA 190 IEIYEQVGAN 200 TMDNPLLKYS 210 AKDYFFKAAL 220 CHFIVDELNA 230 KLALEKYEEM 240 FPAFTDSREC 250 KLLKKLLEAH 260 EEQNSEAYTE 270 AVKEFDSISR 280 LDQWLTTMLL 290 RIKKSIQGDG EGDGDLK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030425 dendrite
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0043025 neuronal cell body
Cellular Component GO:0098794 postsynapse
Cellular Component GO:0014069 postsynaptic density
Cellular Component GO:0098793 presynapse
Cellular Component GO:0048787 presynaptic active zone membrane
Cellular Component GO:0042734 presynaptic membrane
Cellular Component GO:0045202 synapse
Cellular Component GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex
Cellular Component GO:0043195 terminal bouton
Molecular Function GO:0000149 SNARE binding
Molecular Function GO:0005483 soluble NSF attachment protein activity
Molecular Function GO:0019905 syntaxin binding
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0032984 protein-containing complex disassembly
Biological Process GO:0043462 regulation of ATP-dependent activity
Biological Process GO:0002090 regulation of receptor internalization
Biological Process GO:0010807 regulation of synaptic vesicle priming
Biological Process GO:0035494 SNARE complex disassembly
Biological Process GO:0035249 synaptic transmission, glutamatergic

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.