Search Results
Overview
| Uniprot ID | P85971 |
|---|---|
| Protein Name | 6-phosphogluconolactonase |
| Gene Name | Pgls |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 180 | APIGDSPKPPPQRVT |
Function
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
Protein Sequence
10
MAAPAPGLIS
20
VFSSPQELGA
30
SLAQLVAQRA
40
ASCLEGNRGR
50
FALGLSGGSL
60
VSMLARDLPA
70
ATAPAGPASF
80
ARWTLGFCDE
90
RLVPFDHAES
100
TYGLYRTHLL
110
SKLPIPDSQV
120
LTIDPALPVE
130
DAAEDYARKL
140
RQAFQGDTVP
150
VFDLLILGVG
160
PDGHTCSLFP
170
GHPLLQEREK
180
IVAPIGDSPK
190
PPPQRVTLTL
200
PVLNAAQSVI
210
FVATGEGKAA
220
VLKRILEDQE
230
SALPAAMVQP
240
RTGALCWFLD
250
EAAARLLSVP
FEKHSTL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0017057 | 6-phosphogluconolactonase activity |
| Molecular Function | GO:0048029 | monosaccharide binding |
| Biological Process | GO:0005975 | carbohydrate metabolic process |
| Biological Process | GO:0006098 | pentose-phosphate shunt |
| Biological Process | GO:0009051 | pentose-phosphate shunt, oxidative branch |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.