Search Results
Overview
| Uniprot ID | Q00013 |
|---|---|
| Protein Name | 55 kDa erythrocyte membrane protein |
| Gene Name | MPP1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 247 | PSCSPFGKKKKYKDK |
| 248 | SCSPFGKKKKYKDKY |
| 252 | FGKKKKYKDKYLAKH |
| 323 | YTTRPPRKSEEDGKE |
Function
Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity)
Protein Sequence
10
MTLKASEGES
20
GGSMHTALSD
30
LYLEHLLQKR
40
SRPEAVSHPL
50
NTVTEDMYTN
60
GSPAPGSPAQ
70
VKGQEVRKVR
80
LIQFEKVTEE
90
PMGITLKLNE
100
KQSCTVARIL
110
HGGMIHRQGS
120
LHVGDEILEI
130
NGTNVTNHSV
140
DQLQKAMKET
150
KGMISLKVIP
160
NQQSRLPALQ
170
MFMRAQFDYD
180
PKKDNLIPCK
190
EAGLKFATGD
200
IIQIINKDDS
210
NWWQGRVEGS
220
SKESAGLIPS
230
PELQEWRVAS
240
MAQSAPSEAP
250
SCSPFGKKKK
260
YKDKYLAKHS
270
SIFDQLDVVS
280
YEEVVRLPAF
290
KRKTLVLIGA
300
SGVGRSHIKN
310
ALLSQNPEKF
320
VYPVPYTTRP
330
PRKSEEDGKE
340
YHFISTEEMT
350
RNISANEFLE
360
FGSYQGNMFG
370
TKFETVHQIH
380
KQNKIAILDI
390
EPQTLKIVRT
400
AELSPFIVFI
410
APTDQGTQTE
420
ALQQLQKDSE
430
AIRSQYAHYF
440
DLSLVNNGVD
450
ETLKKLQEAF
460
DQACSSPQWV
PVSWVY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005911 | cell-cell junction |
| Cellular Component | GO:0030863 | cortical cytoskeleton |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0032420 | stereocilium |
| Molecular Function | GO:0004385 | GMP kinase activity |
| Molecular Function | GO:0005102 | signaling receptor binding |
| Biological Process | GO:0090022 | regulation of neutrophil chemotaxis |
| Biological Process | GO:0034405 | response to fluid shear stress |
| Biological Process | GO:0007165 | signal transduction |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.