Search Results
Overview
| Uniprot ID | Q02356 |
|---|---|
| Protein Name | AMP deaminase 2 |
| Gene Name | Ampd2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 127 | PDILLRAKQDFLKTD |
Function
AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle (By similarity)
Protein Sequence
10
MASYPGPGKS
20
KAKYPFKKRA
30
SLQASAAAPE
40
ARSGLGASPL
50
QSARSLPGTA
60
PCLKHFPLDL
70
RTSMDGKCKE
80
IAEELFSRSL
90
AESELRSAPY
100
EFPEESPIEQ
110
LEERRQRLER
120
QISQDVKLEP
130
DILLRAKQDF
140
LKTDSDSDLQ
150
LYKEQGEGQG
160
DRGLWERDVV
170
LEREFQRVII
180
SGEEKCGVPF
190
TDLLDAAKSV
200
VRALFIREKY
210
MALSLQSFCP
220
TTRRYLQQLA
230
EKPLETRTYE
240
QSPDTPVSAD
250
APVHPPALEQ
260
HPYEHCEPST
270
MPGDLGLGLR
280
MVRGVVHVYT
290
RRDPDEHCPE
300
VELPYPDLQE
310
FVADVNVLMA
320
LIINGPIKSF
330
CYRRLQYLSS
340
KFQMHVLLNE
350
MKELAAQKKV
360
PHRDFYNIRK
370
VDTHIHASSC
380
MNQKHLLRFI
390
KRAMKRHLEE
400
IVHVEQGREQ
410
TLREVFESMN
420
LTAYDLSVDT
430
LDVHADRNTF
440
HRFDKFNAKY
450
NPIGESVLRE
460
IFIKTDNKIS
470
GKYFAHIIKE
480
VMSDLEESKY
490
QNAELRLSIY
500
GRSRDEWDKL
510
ARWAVNHRVH
520
SPNVRWLVQV
530
PRLFDVYRTK
540
GQLANFQEML
550
ENIFLPLFEA
560
TVHPASHPEL
570
HLFLEHVDGF
580
DSVDDESKPE
590
NHVFNLESPL
600
PEAWVEEDNP
610
PYAYYLYYTF
620
ANMAMLNHLR
630
RQRGFHTFVL
640
RPHCGEAGPI
650
HHLVSAFMLA
660
ENISHGLLLR
670
KAPVLQYLYY
680
LAQIGIAMSP
690
LSNNSLFLSY
700
HRNPLPEYLS
710
RGLMVSLSTD
720
DPLQFHFTKE
730
PLMEEYSIAT
740
QVWKLSSCDM
750
CELARNSVLM
760
SGFSHKVKSH
770
WLGPNYTKEG
780
PEGNDIRRTN
790
VPDIRVGYRY
800
ETLCQELALI
810
TQAVQSEMLE
820
TIPEEVGIVM
SPGP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0003876 | AMP deaminase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0046033 | AMP metabolic process |
| Biological Process | GO:0046034 | ATP metabolic process |
| Biological Process | GO:0042632 | cholesterol homeostasis |
| Biological Process | GO:0052652 | cyclic purine nucleotide metabolic process |
| Biological Process | GO:0097009 | energy homeostasis |
| Biological Process | GO:0032263 | GMP salvage |
| Biological Process | GO:0046039 | GTP metabolic process |
| Biological Process | GO:0006188 | IMP biosynthetic process |
| Biological Process | GO:0032264 | IMP salvage |
| Biological Process | GO:0009117 | nucleotide metabolic process |
| Biological Process | GO:0072015 | podocyte development |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.