Search Results
Overview
| Uniprot ID | Q06889 |
|---|---|
| Protein Name | Early growth response protein 3 |
| Gene Name | EGR3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 267 | KYPNRPSKTPLHERP |
Function
Probable transcription factor involved in muscle spindle development
Protein Sequence
10
MTGKLAEKLP
20
VTMSSLLNQL
30
PDNLYPEEIP
40
SALNLFSGSS
50
DSVVHYNQMA
60
TENVMDIGLT
70
NEKPNPELSY
80
SGSFQPAPGN
90
KTVTYLGKFA
100
FDSPSNWCQD
110
NIISLMSAGI
120
LGVPPASGAL
130
STQTSTASMV
140
QPPQGDVEAM
150
YPALPPYSNC
160
GDLYSEPVSF
170
HDPQGNPGLA
180
YSPQDYQSAK
190
PALDSNLFPM
200
IPDYNLYHHP
210
NDMGSIPEHK
220
PFQGMDPIRV
230
NPPPITPLET
240
IKAFKDKQIH
250
PGFGSLPQPP
260
LTLKPIRPRK
270
YPNRPSKTPL
280
HERPHACPAE
290
GCDRRFSRSD
300
ELTRHLRIHT
310
GHKPFQCRIC
320
MRSFSRSDHL
330
TTHIRTHTGE
340
KPFACEFCGR
350
KFARSDERKR
360
HAKIHLKQKE
370
KKAEKGGAPS
380
ASSAPPVSLA
PVVTTCA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Molecular Function | GO:1990837 | sequence-specific double-stranded DNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0002042 | cell migration involved in sprouting angiogenesis |
| Biological Process | GO:0044344 | cellular response to fibroblast growth factor stimulus |
| Biological Process | GO:0035924 | cellular response to vascular endothelial growth factor stimulus |
| Biological Process | GO:0007623 | circadian rhythm |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0035767 | endothelial cell chemotaxis |
| Biological Process | GO:0007517 | muscle organ development |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:0001938 | positive regulation of endothelial cell proliferation |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
Reference
[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.