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Overview

Uniprot IDQ06AT1
Protein NameNeuron-specific calcium-binding protein hippocalcin
Gene NameHPCA
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
174 EEFIRGAKSDPSIVR

Function

Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels. May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases

Protein Sequence

10 MGKQNSKLRP 20 EMLQDLRENT 30 EFSELELQEW 40 YKGFLKDCPT 50 GILNVDEFKK 60 IYANFFPYGD 70 ASKFAEHVFR 80 TFDTNSDGTI 90 DFREFIIALS 100 VTSRGRLEQK 110 LMWAFSMYDL 120 DGNGYISREE 130 MLEIVQAIYK 140 MVSSVMKMPE 150 DESTPEKRTE 160 KIFRQMDTNN 170 DGKLSLEEFI 180 RGAKSDPSIV 190 RLLQCDPSSA SQF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0016020 membrane
Molecular Function GO:0003779 actin binding
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0042802 identical protein binding
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:1901385 regulation of voltage-gated calcium channel activity

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.