Search Results
Overview
| Uniprot ID | Q07717 |
|---|---|
| Protein Name | Beta-2-microglobulin |
| Gene Name | B2M |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 102 | DQYSCRVKHVTLDKP |
| 108 | VKHVTLDKPKIVKWD |
| 110 | HVTLDKPKIVKWDRD |
Function
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity)
Protein Sequence
10
MAPLVALVLL
20
GLLSLSGLDA
30
VARPPKVQVY
40
SRHPAENGKP
50
NYLNCYVSGF
60
HPPQIEIDLL
70
KNGEKMNAEQ
80
SDLSFSKDWS
90
FYLLVHTEFT
100
PNAVDQYSCR
110
VKHVTLDKPK
IVKWDRDH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0031902 | late endosome membrane |
| Cellular Component | GO:0005765 | lysosomal membrane |
| Cellular Component | GO:0042612 | MHC class I protein complex |
| Cellular Component | GO:0042613 | MHC class II protein complex |
| Molecular Function | GO:0023026 | MHC class II protein complex binding |
| Molecular Function | GO:0042605 | peptide antigen binding |
| Biological Process | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II |
| Biological Process | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I |
| Biological Process | GO:0006955 | immune response |
| Biological Process | GO:0002503 | peptide antigen assembly with MHC class II protein complex |
| Biological Process | GO:0050778 | positive regulation of immune response |
| Biological Process | GO:0050870 | positive regulation of T cell activation |
| Biological Process | GO:0010038 | response to metal ion |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.